• The coverage and quality of

  2019-05-04

  

  The coverage and quality of laboratory services throughout Africa is inadequately documented. Quality provided by individual laboratories is questioned, and not all facilities are enrolled in external quality assurance schemes. For example, in 2013, an evaluation of accredited laboratories in sub-Sa

• Preventive chemotherapy for schistosomiasis is rapidly scali

  2019-05-04

  

  Preventive chemotherapy for schistosomiasis is rapidly scaling up worldwide. The global coverage that was less than 10% in 2010 is now higher than 30%, however, the main limitation for the scaling up is the availability of donated drug. In school age children, the age group for which praziquantel i

• HF is associated with the down regulation

  2019-05-04

  

  HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th

• This report illustrates an unusual

  2019-04-30

  

  This report illustrates an unusual case of CMML which transformed to AML rapidly with emergence of the rare e6a2 fusion transcript. The possibility CML in blasts crisis was excluded as the CMML biopsy showed dysgranulopoiesis and lacked Ph chromosome and BCR-ABL1 fusion transcript. We further revie

• direct renin inhibitors The UN Convention on the Rights of P

  2019-04-30

  

  The 2008 UN Convention on the Rights of Persons with Disabilities (CRPD) requires governments to raise awareness of disability and challenge prejudice and discrimination (Article 8), and to ensure equal and effective legal protection against discrimination (Article 5). Earlier global comparative dat

• br Cardiac imaging br Head up tilt testing Head

  2019-04-30

  

  Cardiac imaging Head-up tilt testing Head-up tilt (HUT) testing is recommended to judge an episode of syncope to be likely caused by VF by excluding neurally mediated syncope (NMS). However, NMS may coexist with Brugada syndrome [42]. We conducted HUT testing in 46 patients with type-1 Brugad

• Causative genes for ARVC and their respective

  2019-04-30

  

  Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table

• br Case report A year old woman who

  2019-04-30

  

  Case report A 41-year-old woman who had been fitted with a pacemaker for bradycardia 18 years prior presented for lead extraction on account of device infection. She had a left pectoral dual chamber pacemaker, with two tined leads: an atrial lead of 5524 M (Medtronic, Dublin, Ireland) and a ventr

• br The translational pipeline in biomedicine from bench to

  2019-04-30

  

  The translational pipeline in biomedicine (from bench to bedside) focused the attention of the global research EHop-016 manufacturer on delivery of results to patients. The notion was rapidly accepted, as shown by the training of researchers in translational approaches, the establishment of trans

• En su introducci n Mabel

  2019-04-29

  

  En su introducción, Mabel Moraña muestra la preocupación, cercana Wortmannin Supplier la de Mato, de traer a la mesa el lugar de lo político y lo ideológico en las discusiones de los Cultural Studies que, considera, se habían constituido como bloque de poder teórico, interpretativo y representationa

• Because of restricted availability of primary data this Arti

  2019-04-29

  

  Because of restricted availability of primary data, this Article only provides prevalence estimates for FAS. FAS is characterised by severe neurodevelopmental impairment and distinctive facial dysmorphology; however, in addition to FAS, PAE could cause a spectrum of disorders, including neurodevelop

• A subanalysis of the RE LY trial reported

  2019-04-29

  

  A subanalysis of the RE-LY trial reported important data about the risk of bleeding in Asian patients [40]. In a comparison between Asian and non-Asian patients receiving warfarin, the risks of ischemic stroke and hemorrhagic stroke were twice higher in Asian than in non-Asian patients. It is possib

• The conditions of the breast tissue in men are

  2019-04-29

  

  The conditions of the breast tissue in men are different from those in women owing to a lack of estrogen and progesterone stimulation in men. Breast lobular development is rare in men, resulting in the rarity of diseases related to lobular proliferation in men, such as fibroadenoma, cyst, fibrocysti

• Patients n who developed osteoporosis whilst

  2019-04-29

  

  Patients (n=5) who developed glucagon receptor antagonist whilst taking ibandronate/placebo medication were un-blinded and offered open label ibandronate treatment. After 2 years the randomised treatment was stopped and the treating clinician, depending upon the results of the BMD result at 2 years,

• During the tumor occurrence and metastasis cancer cells can

  2019-04-29

  

  During the tumor occurrence and metastasis, cancer dexamethasone acetate can modulate the immune system of the host to find strategies that enable them to survive from the immune surveillance [41]. Cancer immunoediting is one of the two major strategies to get away from immune surveillance [42]. In

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