• We describe a novel case wherein a

  2019-05-05

  

  We describe a novel case, wherein a patient with AML with inv (16) underwent allogeneic bone marrow transplantation from a related sibling donor which contained a small subpopulation of premalignant stem ctap with trisomy 11. Fourteen years following transplantation, this patient presented with a d

• br Introduction Worldwide trauma is currently

  2019-05-04

  

  Introduction Worldwide, trauma is currently the sixth leading cause of death, accounting for 10% of mortalities. The urogenital system has consistently been shown to be involved in 10% of patients presenting after trauma and is a significant factor in trauma-induced morbidity and mortality. Renal

• Heat shock facilitates the folding of various proteins

  2019-05-04

  

  Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is

• El cap tulo sobre de Jos Agust n expone

  2019-05-04

  

  El capítulo sobre de José Agustín expone las diferencias entre el de Agustín, de 1966, y el de Pacheco, de 1972. Lo que tienen en común ambas obras, aclara el crítico, es que —a diferencia de otras estudiadas en el volumen— no atestiguan momentos de crisis sino “los largos entretiempos que precede

• FH535 In September a high level meeting of

  2019-05-04

  

  In September 2011, a high-level meeting of the UN called for a concerted global response to the growing challenge of non-communicable diseases (NCDs). Subsequently, in 2013, the World Health Assembly adopted a WHO-generated action plan and set a target of 25 × 25: a 25% reduction in premature mortal

• La entrega del n mero

  2019-05-04

  

  La entrega del número 57, correspondiente al segundo semestre de 2013, ofrece la sección Mirador Latinoamericano, donde se abordan distintos aspectos de la cultura y la literatura en nuestra América. En primer lugar, en el artículo “Crítica literaria y opinión pública: polémicas literarias en Colomb

• Nesta perspectiva enquanto o governo Humalla

  2019-05-04

  

  Nesta perspectiva, enquanto o governo Humalla anunciou uma lista de novos projetos mineiros de valor superior GLPG0634 U$ 41 bilhões, dados da Defensoría del Pueblo registraram 210 conflitos sociais em janeiro de 2015 no país, dos quais 140 de natureza socioambiental. Até meados de 2015, contabiliza

• The coverage and quality of

  2019-05-04

  

  The coverage and quality of laboratory services throughout Africa is inadequately documented. Quality provided by individual laboratories is questioned, and not all facilities are enrolled in external quality assurance schemes. For example, in 2013, an evaluation of accredited laboratories in sub-Sa

• Preventive chemotherapy for schistosomiasis is rapidly scali

  2019-05-04

  

  Preventive chemotherapy for schistosomiasis is rapidly scaling up worldwide. The global coverage that was less than 10% in 2010 is now higher than 30%, however, the main limitation for the scaling up is the availability of donated drug. In school age children, the age group for which praziquantel i

• HF is associated with the down regulation

  2019-05-04

  

  HF is associated with the down-regulation of multiple potassium (K) currents (i.e., Ito, IKs, IKr, IK1, and IKATP). The only K channel that is upregulated in HF is the small conductance Ca-activated K (SK) channel. The SK channel was originally found in most neurons. The increase in Cai evoked by th

• This report illustrates an unusual

  2019-04-30

  

  This report illustrates an unusual case of CMML which transformed to AML rapidly with emergence of the rare e6a2 fusion transcript. The possibility CML in blasts crisis was excluded as the CMML biopsy showed dysgranulopoiesis and lacked Ph chromosome and BCR-ABL1 fusion transcript. We further revie

• direct renin inhibitors The UN Convention on the Rights of P

  2019-04-30

  

  The 2008 UN Convention on the Rights of Persons with Disabilities (CRPD) requires governments to raise awareness of disability and challenge prejudice and discrimination (Article 8), and to ensure equal and effective legal protection against discrimination (Article 5). Earlier global comparative dat

• br Cardiac imaging br Head up tilt testing Head

  2019-04-30

  

  Cardiac imaging Head-up tilt testing Head-up tilt (HUT) testing is recommended to judge an episode of syncope to be likely caused by VF by excluding neurally mediated syncope (NMS). However, NMS may coexist with Brugada syndrome [42]. We conducted HUT testing in 46 patients with type-1 Brugad

• Causative genes for ARVC and their respective

  2019-04-30

  

  Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table

• br Case report A year old woman who

  2019-04-30

  

  Case report A 41-year-old woman who had been fitted with a pacemaker for bradycardia 18 years prior presented for lead extraction on account of device infection. She had a left pectoral dual chamber pacemaker, with two tined leads: an atrial lead of 5524 M (Medtronic, Dublin, Ireland) and a ventr

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