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Examples of numerically generated vortices and their
2019-05-15
Examples of numerically generated vortices and their organizing centers in 3-D excitable media are illustrated in Fig. 1. Panels a to d show 4 different configurations of 3-D scroll waves that were computed using the FitzHugh–Nagumo model [39,40]. Panel a shows an example of the simplest configurati
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In another study Lopez and associates found
2019-05-15
In another study Lopez and associates found that patients with chronic heart failure receiving torsemide, a loop diuretic that inhibits the enzyme involved in the myocardial extracellular generation of collagen type I molecules (i.e., procollagen type I carboxy-terminal proteinase or PCP), had reduc
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br Homing of DTCs to the
2019-05-15
Homing of DTCs to the HSC niche The HSC niche is a complex microenvironment comprised of many cell types, including endothelial cells, adipocytes, osteoclasts, osteomacs, and BB-94 of osteoblastic lineage [5]. A healthy HSC niche provides homing signals to healthy HSCs in order to promote their
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It is important to know
2019-05-15
It is important to know whether pilsicainide can be used as a therapeutic agent for LQT2 patients; and if so, we should determine the types of LQT2 mutation carriers to whom pilsicainide could be administered. As shown in Fig. 8, we examined the effects of pilsicainide on two mutant hERG proteins, G
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De hecho la desordenada colecci n
2019-05-14
De hecho, la desordenada colección de los datos etnográficos se encuentra varias veces en conflicto con la propuesta de un proyecto sistemático que el fraile busca plantear, sin éxito, en el exordio de su obra. En las primeras páginas de la Relación, Pané esboza los confines de un modelo hermenéutic
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In several Western reports from large
2019-05-14
In several Western reports from large-scale comparative studies and epidemiological surveys, there was no significant difference in the incidence of thromboembolism between paroxysmal and persistent AF patients [46,47]. Data from our institution suggested that the incidence of cardiogenic thromboemb
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RANK RANKL The RANK RANKL signaling pathway is a
2019-05-14
RANK/RANKL: The RANK/RANKL signaling pathway is a critical component of both normal and malignant bone remodeling. RANK is a transmembrane signaling receptor and a member of the tumor necrosis receptor (TNF) superfamily that is found on the surface of OCL precursors [43,44]. RANK ligand (RANKL) is e
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br Material and methods br Results br
2019-05-14
Material and methods Results Discussion Previously, various small studies reported that CRT is an effective therapy in patients with NAHF [7,10–15]. These studies demonstrated favorable outcomes in patients treated with CRT, including the ability to wean patients from intravenous inotropes
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En este mismo orden de
2019-05-14
En este mismo orden de ideas, Brian McHale comenta que: Pons señala: Con esto, Pons reconoce que las novelas históricas contemporáneas de la región “no sólo plantean el problema de incluir en la reescritura de la historia lo excluido, lo silenciado, olvidado y reprimido por y en la historia, sino
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br Conclusion br Conflict of
2019-05-13
Conclusion Conflict of interest This work was supported by Medtronic Japan. MN received honoraria from Medtronic Japan, St. Jude Medical Japan and Boston Scientific Japan. YE and TI received honoraria from Medtronic Japan. HS received honoraria from Japan Lifeline. YA, TT, and KK are employees
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Bepridil is a multichannel blocker suggesting that
2019-05-13
Bepridil is a multichannel blocker, suggesting that its pharmacological effects on cardiac myocytes are exerted by blocking Na [21], Ca [22], and K [23–25] channels. It has recently been reported that bepridil has a cardioprotective effect [26] by opening ATP-dependent K chenodeoxycholic acid in mi
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Ion Channel Compound Library Notably it is also reported tha
2019-05-13
Notably, it is also reported that changes in lipoprotein lipase (LPL) activity, HSL activity, and cAMP accumulation in WAT and BAT after ethanol exposure differ depending on the dose and route of ethanol exposure and tissue type. Moreover, a recent study also found that chronic feeding plus alcohol
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Maharaj K Bhan s accompanying Comment correctly identifies t
2019-05-13
Maharaj K Bhan\'s accompanying Comment correctly identifies that the main need is to obtain estimates on cause-specific mortality that are specific to each district. In particular, improved understanding is needed of how three causes, which account for 80% of neonatal deaths (birth asphyxia or traum
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Entre los cronistas y sin
2019-05-13
Entre los cronistas, y sin dejar atrás esta concepción de la naturaleza y sin que se perciba un mayor conflicto, se advierte, en mayor o menor medida, un acentuado interés por los seres naturales y las “causas segundas”. La razón de esta falta de conflicto frontal obedece, por un lado, al reconocimi
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Express o territorial desta expans
2019-05-13
Expressão territorial desta expansão, no início dos anos 1990 as concessões mineiras ocupavam 2.3 milhões de hectares, enquanto na atualidade, beiram 25 milhões. A atividade deixou de se concentrar nas alturas andinas expandindo‐se para os vales, order Z-DEVD-FMK costa e inclusive a Amazônia. Há dep
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