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A Framework Convention on Global Health FCGH supported by ci
2019-05-22
A Framework Convention on Global Health (FCGH)—supported by civil society and global leaders—should become the centrepiece of this endeavour (). It would reform global governance for health to enhance accountability, transparency, and civil society participation and protect the right to health in tr
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Fig shows an example of RNRVAS in a dual
2019-05-22
Fig. 3 shows an example of RNRVAS in a dual-chamber pacemaker recipient with sinus node disease, with the pacemaker set in rate adaptive DDI-R mode pacing with an AV interval of 300ms and lower rate limit of 60ppm. The tracing shows sensor-driven DDIR pacing at 80bpm (V–V purchase LDE225 length=750
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br Results br Discussion Atrial fibrillation is widely
2019-05-22
Results Discussion Atrial fibrillation is widely recognized as the most common sustained arrhythmia. The risk of AF development may be determined by evaluating the patients’ age, sex, underlying LJI308 disease, other medical illnesses, and echocardiographic findings. However, better predictor
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Regarding patients with a lower annual risk
2019-05-22
Regarding patients with a lower annual risk of thromboembolism ( Management of direct acting oral anticoagulants during pacemaker insertion There are less data available regarding management of DOACs peri-procedurally. The general principle is that PM/ICD implantation is considered a low bleeding
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br Conflict of Interest br Acknowledgments br
2019-05-22
Conflict of Interest Acknowledgments Introduction Human ether-a-go-go-related gene (hERG) encodes the alpha subunit of the rapidly-activating delayed-rectifier K+ channel, which plays a pivotal role in repolarization of cardiac action potentials (APs) [1]. Most of mutant hERG proteins causi
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br Es curioso observar que
2019-05-22
Es curioso observar que en el terreno de la crítica musical, la tarea fundamental es evidentemente depurar la teoría de todo aquello que obstaculiza la formulación precisa de los elementos esenciales de la música. Sin embargo, cuando se trata de estudiar el tema de la música en la literatura, nada
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The goals of Vision the global initiative
2019-05-22
The goals of Vision 2020—the global initiative to eliminate avoidable blindness by 2020—include increasing cataract surgical rate and cataract surgical coverage. However, quality must not be sacrificed for quantity. The final visual outcome matters, both to the individual patient and to the communit
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will be remembered as an exceptional year
2019-05-22
2013 will be remembered as an exceptional year in shaping our strategy to control HIV/AIDS. Indeed, a few weeks after the 30th anniversary of the discovery of the virus, a decisive step was made in deciding how to use antiretroviral therapy (ART) for treatment and prevention worldwide. New WHO publi
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A second methodological issue concerns the accuracy of the e
2019-05-21
A second methodological issue concerns the accuracy of the exposure measurement. Without accurate measurement, different methods for calculating attributable risk that are equivalent in theory are not guaranteed to give compatible results in practice. Previous experience with carcinogenic infections
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South Africa was the first African country
2019-05-21
South Africa was the first African country to implement the seven-valent pneumococcal conjugate vaccine (PCV7) in its routine infant immunisation programme (in 2009), with the novel schedule aligned to WHO\'s recommended Expanded Programme on Immunisation (EPI)—ie, a 2 + 1 schedule with doses at age
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Paralelamente Chucho Hegel increpa al Profesor Sin
2019-05-21
Paralelamente, Chucho Hegel increpa al Profesor: “Sin dejar de ser el mismo, te has convertido en el otro como el blanco que se pinta de negro en el teatro bufo”. Pone, así, sobre el tapete, el que quizá sea el mayor de los demonios contra los que lucha el Profesor, personaje, éste, que deja espacio
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br Hacia finales de los a
2019-05-21
Hacia finales de los años ochenta y en el contexto norteamericano, la gran mayoría de las personas que se incluían en la naciente “cultura gay” —habiéndose apropiado previamente de ese término para autodenominarse contra el patologizante apócope de homosexual— eran varones blancos, pequeños burgue
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br Do we need complete isolation of all
2019-05-21
Do we need complete isolation of all PVs in every patient? Circumferential PVI results in satisfactory outcomes for ablation of paroxysmal AF, and electrical isolation of all PVs is currently a standard approach to the treatment of AF, as recommended by the expert consensus statement [6]. Complet
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br Materials and methods br Results br
2019-05-21
Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology
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br Outstanding questions br Conflict of
2019-05-21
Outstanding questions Conflict of interest Acknowledgments This work was supported by the Dutch Cancer SocietyUL2015-7599 KWF (EZ). Platelets and cancer metastasis Blood platelets play a primary role in wound healing and hemostasis. Since the first observation made (on himself) by the s
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