• In an earlier study we used a questionnaire to

  2019-05-31

  

  In an earlier study, we used a questionnaire to assess musculoskeletal pain in patients with CML who had achieved DMR (MR4.0) and discontinued TKI treatment, including IM, nilotinib, and dasatinib [5]. Nine out of the 27 patients surveyed developed musculoskeletal pain after discontinuing TKIs. In t

• In this study the distribution

  2019-05-31

  

  In this study, the distribution of LPs was also analyzed. Similar to previously published data, there was a tendency that vLPs were more frequently observed in patients with ICM than in patients with NICM. However, the total number of those abnormal ventricular electrograms was less documented than

• We conducted a retrospective analysis to compare a BMD alone

  2019-05-31

  

  We conducted a retrospective analysis to compare a BMD-alone strategy, versus BMD+FRAX® and BMD+FRAX®+TBS screening strategies. To our knowledge, this constitutes the first study to assess the relative contributions of FRAX® and TBS. In our cohort, FRAX®+BMD identified 9 (9%) additional patients at

• br Methods br Results br

  2019-05-30

  

  Methods Results Discussion One of the hallmarks of cancer is the ability of cancer BV6 cost to evade apoptosis. Inhibition of apoptosis not only enhances the survival of cancer cells but also facilitates their escape from chemotherapy [5]. Therefore, apoptosis regulatory mechanisms are pro

• En efecto lecturas atentas de estos textos sabr

  2019-05-30

  

  En efecto, lecturas atentas de estos textos sabrán localizar “lo político” de su empeño signado, más allá de referirse o hacer mención procollagen c proteinase políticas específicas, encontradas al paso en los lugares que visitan y recorren, o de hablar sobre los personajes políticos que conocen; má

• HIV counselling and testing is the

  2019-05-30

  

  HIV counselling and testing is the essential first step to accessing HIV care services and is also recognised as an HIV prevention strategy because knowledge of HIV status reduces risky sexual behaviours. A reduction in the number of sexual partners has been reported, but not a significant increase

• br There is growing recognition that children

  2019-05-30

  

  There is growing recognition that children bear a substantial burden of tuberculosis morbidity and mortality. However, in regions where the diagnosis is contingent on smear microscopy, the burden attributable to children, who usually have paucibacillary disease, is grossly underestimated. The down

• La imagen de la Virgen

  2019-05-29

  

  La imagen de la Virgen de Caacupé junto con sus celebraciones religiosas y su devoción llegó a la ciudad en 1993 en forma de obsequio de una compatriota paraguaya a la agrupación arpa. A partir de entonces, la colectividad incorporó la práctica religiosa devocional no sólo como uno de los actos más

• br En general los resultados electorales de demuestran

  2019-05-29

  

  En general, los resultados electorales de 2011 demuestran la identificación y cercanía lograda entre los movimientos sociales y Ollanta Humala, por lo menos en términos de adhesión electoral, la misma que se mantuvo en el tiempo pues en 2006 también estos sectores le otorgaron su voto. Así, la ele

• br Acknowledgements br Introduction The chronic myeloprolife

  2019-05-29

  

  Acknowledgements Introduction The chronic myeloproliferative neoplasms (MPN) comprise a group of clonal stem cell disorders with a high prevalence of the JAK2 V617F mutation (JAK2+) causing excessive production of mature blood cells. Transformation to acute myeloid leukemia (AML) is seen in 2–

• Our patient a year old woman arrived

  2019-05-29

  

  Our patient (a 24-year-old woman) arrived in Italy from Eastern Europe in March 2013 as an illegal immigrant. Three months later she was admitted to our hospital. Her blood counts were as follows: leukocytes 410.7×109/L, platelets 391×109/L, Hb 11g/dl, with immature myeloid bch at differential count

• The increasing complexity and demands of

  2019-05-29

  

  The increasing complexity and demands of the proper diagnosis and management of patients with inherited cardiovascular disease create an opportunity for the development of specialized training for clinical electrophysiologists interested in the care of patients with inherited arrhythmias [229]. Such

• LQTS is classified into subtypes LQT to LQT based

  2019-05-29

  

  LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ

• Bisphosphonates significantly reduce or prevent SREs

  2019-05-28

  

  Bisphosphonates significantly reduce or prevent SREs. The use of Zol for patients with bone metastases is currently the gold standard treatment [4]. However, it is still unclear whether Zol contributes to a survival benefit [9]. Niikura et al. recently reported that Zol did not prolong progression-f

• LQT can have numerous clinical manifestations

  2019-05-28

  

  LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise

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