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Data for each assessment point are expressed
2019-06-24
Data for each assessment point are expressed as the mean value plus standard deviation. One tailed paired t-tests were performed to analyze the effects of ibandronate treatment. Significance level was set at p Results The study included 33 patients with a variety of different primary tumors (Table
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br In Sanguinetti et al and Barhanin et
2019-06-24
In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs
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br Conclusions It is now
2019-06-24
Conclusions It is now clear that a number of src kinase inhibitor are involved in inherited bradyarrhythmia. Recent genetic studies have demonstrated that inherited arrhythmia is attributable to many genes with diverse functions. While the precise underlying mechanisms remain to be elucidated; t
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br Therapy for the CPVT
2019-06-24
Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele
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opioid receptors br Conflict of interest br Introduction br
2019-06-24
Conflict of interest Introduction Cholangiocytes Cholangiocytes are epithelial opioid receptors lining the intra and extrahepatic ducts of the three-dimensional network of the biliary tree. Biliary cells comprise approximately 3–5% of cells in the liver and are considered as one of the mai
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Expansion of access to HIV treatment is
2019-06-24
Expansion of access to HIV treatment is a global priority. In July, 2013, UNAIDS, in collaboration with WHO, the Global Fund to fight AIDS, Tuberculosis and Malaria, and the US President\'s Emergency Plan for AIDS Relief (PEPFAR) jointly issued which advocates for a worldwide treatment target of 15
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De cualquier modo la fecha para votar la
2019-06-24
De cualquier modo, la fecha para votar la propuesta del cuatripartito latinoamericano fue programada para el 16 de mayo de 1949. Tras intensos días de discusión, donde se pudieron observar las claras diferencias existentes también entre los países de América Latina, el balance final fue de 26 votos
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In this study we analyzed the biological
2019-06-24
In this study, we analyzed the biological effects of two novel GATA2 mutations, which were identified in adult de novo AML patients. Materials and methods The diagnosis of AML was based on the morphology, histopathology, the expression of leukocyte differentiation ITE and/or the French–American
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Performing an ajmaline test in children is problematic for
2019-06-21
Performing an ajmaline test in children is problematic for 2 reasons. First, the test is apparently less sensitive in children than in adults. In fact, in 1 study, a repeat ajmaline challenge performed after puberty unmasked BrS in 23% of relatives with a previously negative drug test performed duri
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br Conflict of interest br Case presentation
2019-06-21
Conflict of interest Case presentation A 41-year-old man with a history of palpitations refractory to multiple antiarrhythmic agents for several weeks was referred to our department. A 12-lead electrocardiogram (ECG) demonstrated incessant narrow QRS complex tachycardia (cycle length of 580ms)
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br On Nov every year
2019-06-21
On Nov 25 every year, the International Day for the Elimination of Violence Against Women, and the 16 days of activism that follow it, help to draw the world\'s attention to the scourge of intimate partner violence and other forms of gender-based violence and their harmful effects on women\'s heal
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Treatment options for elderly AML must be based on four
2019-06-21
Treatment options for elderly AML must be based on four main factors: patient\'s clinical condition, disease characteristics, patient wishes and social support. Thus, the most frail and oldest among the oldest will have the least net benefit from chemotherapy or hematopoietic transplantation, even i
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We have received funding from the
2019-06-21
We have received funding from the Wellcome Trust to develop a global atlas of podoconiosis. We aim to advance new knowledge on the geographical distribution and spatial epidemiology of the disease. A first step in this work will be to establish the geographical absence of disease by applying an evid
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br Material and methods br
2019-06-21
Material and methods Results Discussion ES-SCLC is a disease with poor prognosis. Treatment outcome has not improved significantly during the last decades despite great efforts have been made. Maintenance therapy has been tried in several clinical trials with the aim to prevent the onset of
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In advanced GIST patients where a course of
2019-06-21
In advanced GIST patients where a course of treatment of Imatinib is interrupted by disease progression, subsequent rechallenge with Imatinib restored tumor control in most patients. In the prospective BFR14 trial, 25 patients with disease progression after interruption of one year of treatment rest
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